Fahrija Skokic, Nesad Hotic, Selma Muratovic, Maida Skokic, Devleta Hadzic, Almira Cosickic, Amela Selimovic, Evlijana Zulic, Alma Meric, Amir Halilbasic


Introduction: Despite growing progress
of perinatal medicine and perinatal care, between 9-19%
of preterm infants are born each year. Improvement in
survival of infants and the reduction in infant mortality
rates is a key role of perinatal quality healthcare.
The Aim: To evaluate the perinatal outcome of
preterm infants in maternity wards of the Federation of
Bosnia and Herzegovina for a period of one year.
Material and methods: Of 22 897 live newborns,
the research criteria matched 669 (2.9%) preterm infants
with complete medical records in ten cantons of
the Federation Bosnia and Herzegovina. We analyzed
data from maternity wards documentation and discharge
letters from tertiary health care centers.
Results: Most deliveries were in the Tuzla and Sarajevo
Canton with 42.5% of preterm infants. The mean
gestational age of preterm infants was 31.4 weeks, with
SD ± 5.34, and the mean birth weight 1295 grams, SD ±
234.2. The mean Apgar score was 4.6 ± 2.1, and in the
fifthminute 6.6 ± 1.9.Of 669 examinees, there were 345
(51.56%) males and 324 (48.44%) females (51.56 vs
2 = 1.19; P = 0.27). By analyzing the frequency
of preterm infant birth rate according toweight categories,
we found a significant difference in some levels of
perinatal health institution, between the 1st and 2nd institutions
levels (1.76% vs 3.01%; P< 0.0001), also between
2nd and 3rd institutions levels (3.01% vs 3.03%; P <
0.0002), and between 1st and 3rd institutions levels
(1.76% vs 3.03%; P < 0.0001). A significant statistical
difference in survival of tested newborns was found in
institutions of 3rd level
2 = 49.25; P < 0.0001 with a
low risk for unfavorable outcome [OR = 0.436; 95%CI
Conclusion: Perinatal outcome of preterm infants
in the Federation Bosnia and Herzegovina significantly
depends on the level of perinatal health care. Survival
rate of infants born in the institutions of the 3rd level
was statistically much higher than the survival rate of
infants who were born in the 1st and the 2nd level institutions.
Key words: preterm infants, perinatal outcome,
preterm birth, regionalization, neonatal mortality.

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