Aleksandar Oroz, Zorana Bokun, Biljana Lazovic, Ognjen Cukic, Svetlana Valjarevic


Introduction: Malignant skin tumors in the majority of cases arise from the squamous  epithelium, although they may occur in other accompanying skin structures, such as skin adnexa (hair follicle, sweat and sebaceous glands), as well as soft tissues participating in the building of skin structure, such as muscles, fibrous, fatty tissue and cartilagе. Those tumors may also have a neuroendocrine origin or may arise from a premalignant lesion (solar keratosis and lentigo maligna). Regardless of their origin, they usually present as a nodule or longstanding, non-healing ulceration. Their early recognition enhances the treatment results and decreases the possibility of complications (invasion of deeper tissue structures and occurrence of regional and distant metastases).

Material and methods: Our retrospective study included 100 patients of both sexes surgically treated for skin malignancy in the Department for Otorhinolaryngology and Maxillofacial surgery of the Clinical Hospital Centre “Zemun” , Belgrade, Serbia.

The goal of this paper is to highlight the frequency of rare malignant tumors compared to the more frequent ones and consider the most appropriate clinical-diagnostic approach as well as the treatment modality for the patient.

Conclusion: Our study has shown that the most frequent tumor of the head and neck skin is basal cell carcinoma.


rare malignant skin tumor, skin tumor frequency, metastases, surgery, therapy.

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DOI: http://dx.doi.org/10.24125/sanamed.v13i3.245


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